Male erectile dysfunction (ED) is treated with megalis pills, a high-dosage drug. Sildenafil citrate, the active component in Viagra, is present in these pills. The phosphodiesterase type 5 (PDE5) inhibitor sildenafil citrate aids in the initiation and maintenance of an erection during sexual stimulation by increasing blood flow to the penis. It is recommended that Megalis be taken 30 to 60 minutes before engaging in sexual activity. Using water, swallow the tablet whole. It cannot be chewed, crushed, or broken.